A Kirksville woman was seriously injured on a motorcycle in Macon County on Friday evening. According to the Missouri State Highway Patrol at around 6:50 pm,  63-year-old Le Ann Jackson of Macon was traveling North on Highway O about 2 and a half miles North of Bevier when she ran off the roadway, overturned and ejected both her and a passenger, 62-year-old Rhonda Hargadine of Kirksville. Hargadine was seriously injured and flown to Columbia.  Jackson was transported to Columbia by ambulance.