The Missouri Department of Health and Senior Services issued a COVID-19 Hotspot Advisory for Randolph, Macon, and Adair counties Wednesday. The Department says disease spread from southwestern and central Missouri is expected to move to the northeast along Highway 63. The Delta variant, which spreads more easily and poses higher risk of hospitalization than prior variants, is believed to be contributing to the increase. In the past 14 days, Randolph County reported 75 total cases, Adair County has reported 69 total cases, and Macon County reported 39 total cases. Vaccination rates are 24.2 percent in Randolph County, 33.3 percent in Adair County, and 28.4 percent in Macon County. Experts say at least 70 to 80 percent of people need immunity to minimize spread within a community. Those who do not to get vaccinated should continue to stay six feet away from others, wear a mask in public, avoid others if they appear sick of if you have symptoms, and wash your hands.